| abstract |
The invention relates to compounds of formula (I) or a pharmaceutically acceptable salt thereof, wherein each of the substituents A, R, R, R, R and R are described herein, or to pharmaceutically acceptable salts and compositions comprising such compounds, as well as to the use of such compounds in the treatment of conditions mediated by 5-HT agonistic activity, such as, but not limited to, reflux gastroesophageal disease, gastrointestinal disease, upset stomach function, non-ulcer dyspepsia, functional dyspepsia, irritable syndrome colon, constipation, dyspepsia, esophagitis, gastroesophageal disease, nausea, central nervous system disease, Alzheimer's disease, cognitive impairment, vomiting, migraine, neurological disease, pain, cardiovascular disorders, heart failure, cardiac arrhythmia or sugar, choking syndrome. |