abstract |
The invention relates to a chimeric hybrid protein monomer-dimer, wherein said protein contains first and second polypeptide chains, where said first polypeptide chain contains at least a portion of an immunoglobulin constant region and a biologically active molecule, and said second polypeptide chain contains at least a portion of a constant region immunoglobulin without a biologically active molecule present in the first chain. The invention also relates to methods of use and methods for producing a chimeric monomer-dimer fusion protein according to the invention. |