abstract |
The present invention relates to modified enzymes GTP-cyclohydrolases II, which exhibit increased specific activity, as well as polynucleotides encoding these enzymes. The present invention also relates to vectors containing these polynucleotides, and host cells containing such vectors. The invention provides a method for producing a modified enzyme and a method for the production of riboflavin, a riboflavin precursor, FMN, FAD or a derivative thereof. |