| abstract |
Descriptions are given of methods and applications for inducing apoptosis of cells, in particular breast cancer cells, involving the administration of antiprogestins, in particular antiprogestin 11β- (4-acetylphenyl) -17β-hydroxy-17α- (1,1,2,2,2-pentafluoroethyl) estra-4,9-dien-3-one or a pharmaceutically acceptable derivative or analog thereof. This invention relates to the treatment of cancer, an indicator of a high risk of occurrence of which is an increased number of tumor cells in the S-phase of the cell cycle, and this treatment involves the administration of antiprogestin, in particular 11β- (4-acetylphenyl) -17β-hydroxy-17α- (1, 1,2,2,2-pentafluoroethyl) estra-4,9-dien-3-one or a pharmaceutically acceptable derivative or analog thereof. |