abstract |
The present invention discloses a method for targeting maytansinoids to a selected cell population, comprising contacting a population of cells or tissue suspected to contain a selected population of cells with a maytansinoid conjugate and a cell-binding agent in which one or more maytansinoids are covalently linked to a cell-binding agent via a non-cleavable linker and the cell binding agent binds to the cells of the selected cell population. |