abstract |
Compounds of the formula where Ar, Ar, X, R and m are described are as defined herein, or a pharmaceutically acceptable salt thereof (“tetrahydropyridine compound”); compositions containing an effective amount of a tetrahydropyridine compound; and methods for treating or preventing pain, UI, ulcers, IBD, IBS, addictive disorders, Parkinson's disease, parkinsonism, anxiety, epilepsy, stroke, seizures, pruritus, psychosis, cognitive impairment, memory impairment, impaired brain function, Huntington’s chorea, ALS, dementia, retinopathy, myotonic spasm, migraine, vomiting, dyskinesia, or depression in an animal, comprising administering to the animal according to indications of an effective amount of a tetrahydropyridine compound. |