| abstract |
The present invention relates to blocking, inhibiting, reducing, suppressing or neutralizing the activity of the polypeptide molecules of IL-22, IL-20 or IL-20 and IL-22. IL-20 and IL-22 are cytokines that are involved in inflammatory processes and in the pathogenesis of human disease. IL-22RA (zcytor11) is a common receptor for IL-20 and IL-22. The present invention relates to antibodies against IL-22RA and their binding partners, as well as to methods of suppressing IL-22 or IL-20 and IL-22 using such antibodies and binding partners. |