| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69c91bbf0395db010b4806f50d808c4e |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-24 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-12 |
| filingDate |
2004-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7691e8c2d5b57eb837c03e673f4da716
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eddc4747975e850ccf3db0bc644b1756
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ea6ada2ba4eb9b5f730cafd2af74b488
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f90e2efbc6545363ee5de1cb82085407
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11523e8af58a0e7e625fc6daee3e7546
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_37c77c04d3cedd35a210e90a8d2ed9e5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5743dbca64622aaf87c6dcc39b75350 |
| publicationDate |
2007-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EA-008883-B1 |
| titleOfInvention |
A METHOD FOR OBTAINING A CHIRALLY PURE N- (TRANS-4-ISOPROPYLCYCLOGEXYLKARBONIL) -D-PHYNALANINE AND ITS CRYSTALLINE MODIFICATIONS |
| abstract |
The invention relates to N- (trans-4-isopropylcyclohexylcarbonyl) -D-phenylalanine (nateglinide) in a new crystalline form "G" and a method for its preparation. Also provided is a method for preparing chirally pure nateglinide by treating its lower alkyl ester with a base to form an alkali metal salt and liberating the product from this salt by appropriate acid addition. Another aspect of the invention is a process for preparing nateglinide in the "H" crystalline form from other crystalline modifications of nateglinide. |
| priorityDate |
2003-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |