| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1fe84084eed7f266d099c2d96e0eab56 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-71
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| filingDate |
2004-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2728a5459ec3753c89e5677f7d0cac34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2cde7c97014d6f4d976cb7e1f99fa169 |
| publicationDate |
2007-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EA-008827-B1 |
| titleOfInvention |
CLEANING OPTIONS HER-2 |
| abstract |
The present invention provides a new method for purifying a protein of the EGFR family obtained from insect cell cultures. The process contains the successive steps of a) diafiltration and replacement of the culture medium with a buffer; b) immobilized metal affinity chromatography (IMAC); c) size exclusion chromatography (SEC), f) anion exchange chromatography (AIE). The method also provides an immunogenic variant of the HER-2 protein, for which the purification process is mainly adapted, as well as the means to produce this variant. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2610667-C2 |
| priorityDate |
2003-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |