abstract |
The invention describes substituted at position 6 indolinone derivatives of the general formula (I) in which R-R and X have the meanings indicated in claim 1, their tautomers, enantiomers, diastereomers, their mixtures and their salts, especially their physiologically compatible salts, which have valuable pharmacological properties, first of all, an inhibitory effect on various receptor tyrosine kinases, as well as on the proliferation of endothelial cells and various tumor cells, and also drugs containing these compounds are described , the use of these compounds and the method for their preparation. |