abstract |
A container containing a closure coated with an inert fluorinated material and a liquid pharmaceutical composition. In particular, the container includes a Teflon-coated closure and contains an interferon-β composition without SAC, having the following composition: 30-100 μg / ml interferon-β, isotonic agent, 0.1-2 mg / ml poloxamer 188, at least 0.12 mg / ml L-methionine and a buffer solution capable of maintaining the pH of the liquid composition at a value of from 3.0 to 4.0. |