abstract |
Compounds of formula (IA) or (IB), where W is HO (C = O) -, HONH (C = O) - or H (C = O) N (OH) -; X represents āOā or āSā; and R, R and R have the meanings given in the description and claims are inhibitors of matrix metalloproteinases, in particular MMP9 and / or MMP12. |