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filingDate 2002-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2566935d77b8330bdfab736fcfeb6a1a
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publicationDate 2006-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EA-007004-B1
titleOfInvention REVERSE TRANSCRIPTASES NON-NUCLEOSIDE INHIBITORS AS ANTAGONISTS OF PROLIFERATION AND CELL DIFFERENTIATION INDUCERS
abstract The invention relates to the use of reverse transcriptase (RT) inhibitor compounds for the preparation of pharmaceutical compositions for counteracting the loss of cell differentiation in cancer and non-cancer pathologies, these compounds being able to bind to the hydrophobic pocket of the p66 RT subunit. The following compounds are particularly preferred for such use: nevirapine, efavirenz, delavirdine, their corresponding salts and / or pharmaceutically acceptable derivatives.
priorityDate 2001-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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