| abstract |
The compound of formula (I) in which R represents aryl group, heteroaryl group or alkyl group, optionally substituted, or a group of formula - (CO) -CRRNRR, in which R, R, R and R take the values specified in the description, R represents a hydrogen atom or an alkyl group, R represents a hydrogen atom or an optionally substituted alkyl group, R represents a saturated or unsaturated, 7 to 15-membered bicyclic system or an optionally substituted alkyl group, or R and R together with the carbon atom carrying them, forming t is saturated or unsaturated, a 3-18 membered mono-, bi- or tricyclic system, optionally containing one or more heteroatoms selected from O, S, and N, and optionally substituted, n is 0, 1, or 2, Ar is an aryl or heteroaryl group, an R group represents an amino group, a guanidino group, a cyano group and an amidino group of the group which is optionally substituted, its optical isomers, as well as its addition salts with a pharmaceutically acceptable acid. Medicines. |