abstract |
According to the present invention, there is provided a method for producing an orally administered calcium composition, comprising the steps of (1) obtaining a physiologically tolerable calcium compound in the form of particles, having an average particle size in the range of 3 to 40 μm, having a crystalline structure and having a surface area of 0.1 to 1.2 m / g; (2) mix the specified calcium compound with a water-soluble diluent and an aqueous solution of a water-soluble binder in a fluid-bed granulation apparatus and dry the mixture to obtain a first granulate; (3) it is possible to mix said first granulate with one or more additional components to form a second granulate; and (4) optionally pressing said first or second granulate to form tablets. |