abstract |
3,4,5-Trisubstituted aryl nitron compounds and pharmaceutical compositions containing such compounds are provided. The 3,4,5-trisubstituted arylnitron compounds have the formula (I), wherein R-R are as defined herein. The claimed compounds can be used as therapeutic agents for the treatment in mammals of conditions associated with inflammation, such as arthritis, as well as analytical reagents for the detection of free radicals. |