http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EA-004707-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ddd73f31f6b04300210aa01581405e43 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-06 |
| filingDate | 2000-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_828c5de29a80b176281179807ba32d60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0552b6a2ad665dd5fd5aad9480353b20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bda3792a9cd83c9d384e7699a0ba2468 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f005d074766870a39542264ddc202a75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a5e6a3653347238ddc9529aa9f693c4 |
| publicationDate | 2004-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EA-004707-B1 |
| titleOfInvention | DINUCLEOTIDE CRYSTALS |
| abstract | The present invention relates to crystals of P- (2'-deoxycytidine 5 '-) P- (uridine 5' -) tetraphosphate (dCP4U) or its salts and to a method for producing crystals. The present invention also provides a process for preparing dCP4U comprising the reaction of uridine 5'-monophosphate (UMP), 2'-deoxycytidine 5'-monophosphate (dCMP), diphenylphosphochloridate (DPC) and pyrophosphate (PPi). The dCP4U crystals according to the method of the present invention have high purity and high stability, and are not hygroscopic as compared to the freeze-dried product, and therefore serve as a useful raw material for the preparation of drugs. The method of obtaining dCP4U in accordance with the present invention allows the use of inexpensive UMP as a raw material and provides a high yield. Thus, the process is suitable for large-scale synthesis of dCP4U. |
| priorityDate | 1999-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 68.