abstract |
The present invention relates to compounds that inhibit IMPDH. The present invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting the activity of the IMPDH enzyme and, therefore, can best be used as therapeutic agents for IMPDH-mediated processes. This invention also relates to methods of inhibiting IMPDH activity using the compounds of the present invention and related compounds. |