| abstract |
The invention describes substituted indolinones of the general formula (I) in which R-R and X have the meanings indicated in claim 1, their isomers and their salts, especially their physiologically acceptable salts. The proposed compounds possess valuable pharmacological properties, primarily an inhibitory effect on various kinases and cyclin / CDK complexes, as well as on the proliferation of various tumor cells. also describes drugs containing these compounds, the use of these compounds and method for their preparation. |