| abstract |
Describes the use in the manufacture of a medicament for use as an analgesic, a compound that is an alpha-aminoamide of formula (I) in which A represents a group - (CH) -, - (CH) -X- or - (CH) -O- where m is an integer from 1 to 4, n is zero or an integer from 1 to 4, X is —S— or —NH—, av is zero or an integer from 1 to 5; s is 1 or 2; R represents a furyl, thienyl or pyridyl ring or phenyl ring; R 1 is hydrogen or C 1-6 alkyl; one of R and R represents hydrogen, and the other represents hydrogen or C 1-6 alkyl optionally substituted with hydroxy or phenyl; or R and R, taken together with the carbon atom to which they are attached, form a C-cycloalkyl ring; or R and Roba are methyl; R 1 represents hydrogen or a C 1-6 alkyl group; or a pharmaceutically acceptable salt thereof. |