| abstract |
According to the present invention, there is provided a compound of formula (I) and pharmaceutically acceptable salts thereof, wherein R 1 is C 1-6 alkyl; R 1 is hydrogen, C 1-6 alkyl, haloC 1-6 alkyl or phenyl; R 1 is hydrogen or halogen; R and R are independently hydrogen, C-C1-6alkyl or haloC-C1-6alkyl; and n is one, two or three. These compounds are useful as analgesics or anti-inflammatory agents, or in the treatment of a mammal, especially humans, cardiovascular diseases, allergic disorders, angiogenesis, disorders of the central nervous system, vomiting, gastrointestinal disorders, solar erythema, urinary incontinence or diseases, disorders or adverse conditions caused by Helicobacter pylori or the like. Intermediates are also described for preparing compounds of formula (I). |