| abstract |
A class of 1,2,4-triazolo [4,3-b] pyridazine derivatives substituted or condensed with a 7.8 ring having a possible cycloalkyl, phenyl or heteroaryl substituent at position 3 and a substituted alkoxy particle at position 6, which are selective ligands for GABA receptors, in particular, exhibiting a high affinity for their α2 and / or α3 subunits, and, accordingly, being useful in the treatment and / or prevention of disorders of the central nervous system, including anxiety and convulsions. |