| abstract |
New benzimidazole derivatives are provided, represented by the formula wherein A represents a bond or an alkylene or alkenylene group; pharmaceutical compositions based on them, a method for their preparation and use in a method for the prevention and treatment of impaired glucose tolerance, diabetes, diabetic complications, insulin resistance syndrome, hyperlipidemia, atherosclerosis, cardiovascular disorders, hyperglycemia or hypertension; or angina pectoris, hypertension, pulmonary hypertension, congestive heart failure, glomerulopathy, tubulointerstitial disorders, renal failure, atherosclerosis, angiostenosis, distal angiopathy, cerebral hemorrhage, chronic reversible obstruction, allergic rhinitis, urticaria, urticaria, , diabetic complications, nephritis, tumor cachexia, or restenosis after PTCA. |