| abstract |
The compound of formula (I), where R is selected from the group consisting of phenyl, substituted by one or more than one halogen atom, naphthyl and naphthyl, substituted by one or more than one halogen atom; R is selected from the group consisting of -NH and -NHC (= O) R; R selected from the group consisting of -NRR, -NHC (= O) R and hydrogen, R selected from the group consisting of hydrogen, -Salkyl, -Salkyl, substituted by one or more than one halogen atom, -CN, -CHOH, -CHOR and - CHS (O) R; where R 1 is C 1-6 alkyl or C 1-6 cycloalkyl, and R 3 and R 5, which may be the same or different, are selected from hydrogen and C 1-6 alkyl, or together with the nitrogen atom to which they are attached, form a 6-membered nitrogen-containing heterocycle, and this heterocycle may be further substituted by one or more than one Calkyl; R is selected from Calkyl or Calkyl, substituted by one or more than one halogen atom; x is an integer zero, one, or two; and its pharmaceutically acceptable derivatives; with the proviso that R is not (a) when R is -NH and R and R both are hydrogen |