Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b82316f6c4ce539d2e381c8cdac9b315 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e4a18d0e98b0819456528758c223dcb3 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F220-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-787 |
filingDate |
1998-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4bfff66135e1457025a454f910ebca35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a51bb7a861e2aa61624d5877395a775a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_302484b0b99ca2bf1635464ebfd76bbe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_992d208a3ccec389bfd185de441d4789 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f53c4fa6323c76019e728b707045d3e3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a74b0a5729995591f5fbc6ee139b61e7 |
publicationDate |
2001-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EA-002030-B1 |
titleOfInvention |
POLYMERIC DERIVATIVES OF CAMPTOTECINES |
abstract |
Camptothecin water soluble polymeric conjugates include N- (2-hydroxypropyl) methacryloylamide units linked through a spacer of the formula -Gly- (CH) -CO-Gly, where n = 2-8 to the C-20 position of the camptothecin residue. Conjugates have increased anti-tumor activity and less toxicity than free drug. The method for their preparation and the pharmaceutical compositions containing them are also described. |
priorityDate |
1997-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |