http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EA-001000-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eb203ae1b0dea7ccd5a6bde823d53ef0 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0202 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0812 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-02 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-02 |
| filingDate | 1996-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9412b097dbeb42ffee337acf9698fff http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0260d9bf503b256e02cce066950cb79f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3cb1a9a2fd7c9e4291ec9eab6183a198 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d79f95c61db7cec87caf2a359ad51435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f4f9e6ec6917a24fd84d80da0aa00cd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a0d79d8e224b3b93b6c997287180d728 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f15faa16d58d635aca9ad0ec218b6890 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9132129e8253bea8a1c3a8426d7f81f |
| publicationDate | 2000-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EA-001000-B1 |
| titleOfInvention | PEPTIDE DERIVATIVES |
| abstract | 1. A compound represented by the following formula: Y-L-Tyr-Q-NR<1>-CH(R<2>)-CO-X wherein: R<1> represents hydrogen atom; R<2> represents unsubstituted benzyl group; Q represents D-Arg; Y represents one hydrogen atom and C1-6-alkyl group, or Y represents one hydrogen atom and group of formula HN=C(R<3>), wherein R<3> is C1-6-alkyl group; and X represents NR<7>-C(R<8>)(R<9>)(R<10>), wherein R<7> is C1-6-alkyl group, R<8> is carboxy-C1-6-alkyl group or C1-6-alkoxycarbonyl-C1-6-alkyl group, R<9> represents hydrogen atom and R<10> reprsents hydrogen atom, or a salt thereof. 2. The compound as claimed in claim 1 which has the following formula: N-methyl-Tyr-D-Arg-Phe-N(CH3)-CH2-CH2-COOH or the ester thereof of the formula N-methyl-Tyr-D-Arg-Phe-N(CH3)-CH2-CH2-CO-O-C1-6-alkyl, or their salt. 3. The compound or the salt thereof as claimed in claim 1 which has the following formula: HN=C(CH3)-L-Tyr-D-Arg-L-Phe-N(CH3)-CH2-CH2-COOH. 4. The salt of the compound according to any of claims 1-3, is hydrochloride or acetate. 5. A medicament comprising the compound or the salt according to any of claims 1-3. 6. An anaesthetic pharmaceutical composition comprising as an active ingredient the compound or the salt thereof according to any of claims 1-3. 7. Use of the compound or the salt thereof according to any of claims 1-3 for manufacture of the pharmaceutical composition according to claim 6. 8. A method for prevention and/or therapeutic treatment of pain, comprising a step of administering to an mammal an effective amount of the compound or the salt thereof according to any of claims 1-3. |
| priorityDate | 1995-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 114.