http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EA-000758-B1

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filingDate 1996-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1950d88feb5432964d4514c33c86ba62
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publicationDate 2000-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EA-000758-B1
titleOfInvention METHOD OF TREATMENT OF BIPOLAR DISORDER
abstract 1. A method for treating Bipolar Disorder comprising administering to a mammal in need of such treatment from about 1 mg to about 20 mg per day of olanzapine, or a pharmaceutically acceptable salt thereof. 2. A method of claim 1 wherein the Bipolar Disorder is Bipolar Disorder I. 3. A method of claim 1 wherein the Bipolar Disorder is Bipolar Disorder II. 4. A method of claim 1 wherein olanzapine is Form II olanzapine polymorph having a typical x-ray diffraction pattern as follows, wherein d represents the interplanar spacing: d 10.2689 8.577 7.4721 7.125 6.1459 6.071 5.4849 5.2181 5.1251 4.9874 4.7665 4.7158 4.4787 4.3307 4.2294 4.141 3.9873 3.7206 3.5645 3.5366 3.3828 3.2516 3.134 3.0848 3.0638 3.0111 2.8739 2.8102 2.7217 2.6432 2.6007 5. A method of claim 2 wherein olanzapine is Form II olanzapine polymorph having a typical x-ray diffraction pattern as follows, wherein d represents the interplanar spacing: d 10.2689 8.577 7.4721 7.125 6.1459 6.071 5.4849 5.2181 5.1251 4.9874 4.7665 4.7158 4.4787 4.3307 4.2294 4.141 3.9873 3.7206 3.5645 3.5366 3.3828 3.2516 3.134 3.0848 3.0638 3.0111 2.8739 2.8102 2.7217 2.6432 2.6007 6. A method of claim 3 wherein olanzapine is Form II olanzapine polymorph having a typical x-ray diffraction pattern as follows, wherein d represents the interplanar spacing: d 10.2689 8.577 7.4721 7.125 6.1459 6.071 5.4849 5.2181 5.1251 4.9874 4.7665 4.7158 4.4787 4.3307 4.2294 4.141 3.9873 3.7206 3.5645 3.5366 3.3828 3.2516 3.134 3.0848 3.0638 3.0111 2.8739 2.8102 2.7217 2.6432 2.6007 7. A method of claim 4 wherein the effective amount is from about 1 mg to about 25 mg per day. 8. A method for treating Bipolar Disorder, wherein the patient suffering from or susceptible to Bipolar Disorder does not experience mania, comprising administering from about 2.5 mg to about 30 mg per day of olanzapine, or a pharmaceutically acceptable salt thereof to a patient in need thereof. 9. A method of claim 8 wherein olanzapine is Form II. 10. A method for treating Bipolar Disorder, such as a Major Depressive Episode, comprising administering from about 2.5 mg to about 30 mg per day of olanzapine, or a pharmaceutically acceptable salt thereof to a patient in need thereof. 11. A use from about 1 mg to about 25 mg of olanzapine for the manufacture of a medicament for therapeutic application in treating Bipolar isorder. 12. A use of claim 11 wherein the Bipolar Disorder is Major Depressive Episode. 13. A use of claim 11 wherein the Bipolar Disorder is such that the patient does not experience a manic episode.
priorityDate 1996-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 31.