http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DO-P2011000307-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a9e6421e9257148abad101e1ce6c162 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D489-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-08 |
| filingDate | 2011-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e64accdfdcfa2c626a65e9cb49f89107 |
| publicationDate | 2011-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DO-P2011000307-A |
| titleOfInvention | N-ALQUIL-NALTREXONA HALOGENURE PREPARATION PROCEDURE |
| abstract | The invention relates to a new process for the preparation of N-methyl-naltrexone bromide, which comprises at least the steps consisting of: (i) reacting the N-methyl-naltrexone methylsulfate in aqueous solution with a chosen alkaline agent from the group consisting of sodium carbonate, potassium carbonate, calcium carbonate, magnesium carbonate, cesium carbonate, strontium carbonate and their mixtures, for a pH of the aqueous reaction medium between 7 and 10, and then ( ii) reacting the product thus obtained with the hydrobromic acid that is added, for a pH of the aqueous reaction medium between 0.5 and 5, and thus obtaining the bromide of N-methyl-naltrexone. |
| priorityDate | 2006-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 35.