| abstract |
The invention relates to tricyclic N-heteroaryl-carboxamide derivatives containing a benzimidazole moiety, of general formula (I) in which A together with the CN bond of the benzimidazole moiety to which it is condensed, represents a monocyclic heterocycle or a heteroaryl monocyclic 4 to 7 links, containing 1 to 3 heteroatoms chosen from O, S or N, including the nitrogen atom of the benzimidazole moiety; P represents a bicyclic heterocycle or bicyclic heteroaryl of 8, 9, 10 or 11 links, comprising 1 to 6 heteroatoms selected from N, O and S; R1 represents 1 to 4 identical or different atoms or groups; And it represents an oxygen or sulfur atom; R2 represents a hydrogen atom, a halogen atom, a C1 C6 alkyl group, C3 C7 cycloalkyl, C3 C7 cycloalkyl (C1-C3) alkylene, C1 C6 fluoroalkyl or alkoxy C1 C6; R3 represents 1 to 3 identical or different atoms or groups; in the base or acid addition salt state, as well as in the hydrate or solvate state. The invention also relates to a process for preparing the compounds and their application in therapeutic treatments. |