| abstract |
The invention relates to new products of the formula (I): in which Al, A2, A3 and A4 represent CRa or N; R1 and R1 'are such that one represents H, Hal, C1-C3 alkyl, C1-C3 alkoxy, alkyl-OH, CF3, cyano, carboxy or carboxamido; and the other represents H; Hal; CF3; OH; SH; nitro; Not me; NH-OH; NH-CO-H; NH-CO-OH, NH-CO-Oalkyl, NH-CO-NH2; carboxy; CN; CO-NH2; X- (CH2) m-alkyl; X- (CH2) m-cycloalkyl; X- (CH2) m-heterocycloalkyl; X (CH2) m-aryl or X- (CH2) m-heteroaryl with X = single bond, CH2, CH = CH, CH2-O, CH2-NH, CH2-C (O), CH2-C (O) - O, CH2-C (O) -NH, CH2-NH- (CO), CH2-NH-S (O), CH2-NH-S (O) 2, 0, S, NH, OC (O), C (O) -NH, -NH-C (O), -NH-C (O) -C (O) -, -NH-C (O) NH-, NH-CS, NH-S (O) or NH -S (O) 2; m = 0, 1 0 2; either R1 and R'1 form with the C to which they are attached or a radical = O; = S; = N-OH; = N-NH2; = N-NH-CO-NH2, = CH-OH; = Yl- (CH2) m-aryl or = Y1- (CH2) m-heteroaryl, in which Y1 represents CH, CH-CO-, CH-CO-NH, N, NO or N-NH-, with m = 0.1 or 2, or one cycle, R2 and R'2, represent H, halogen, CF3, nitro, cyano, alkyl, hydroxy, mercapto, amino, alkylamino, dialkylamino, alkoxy, alkylthio, free or esterified carboxy, carboxamide , CO-NH (alkyl) and CO N (alkyl) 2, p = 1 to 3 and p '= 1 to 4; Ra represents H; halogen; CF3; hydroxy; mercapto; nitro; Not me; NH-OH; NH-CO-H; NH-CO-NH2; carboxy; CN; CO-NH2; Y- (CH2) n-alkyl; Y- (CH2) n-cycloalkyl, Y (CH2) n-heterocycloalkyl, Y- (CH2) n-aryl or Y- (CH2) n-heteroaryl, with Y = 0, S, NH, OC (O), C (O) -NH, NH-C (O), NH-S (O) or NH-S (O) 2, with n = 0, 1, 2 0 3, |