abstract |
The invention relates to compounds of formula (l) for treating, for example, sexual dysfunction, wherein R1 is optionally substituted C1-6 alkyl, optionally substituted carbocyclyl, optionally substituted heterocyclyl, hydrogen, C1-6 alkoxy, -NR2R3 or -NR4SO2R5, X is the bond (CH2) NO- (CH2) qO- (where and is bound to oxygen); where one or more hydrogen atoms in the X bond can be replaced, independently, by C1-4 alkoxy hydroxy; C1-3 hydroxyalkyl; C3-7 cycloalkyl carbocyclyl heterocyclyl; or by C1-4 alkyl optionally substituted with one or more fluoro or phenyl groups; n is 3, 4, 5, 6 or 7; and q is 2, 3, 4, 5 or 6; and Y is phenyl or pyridyl, each of which may be substituted; or two R8 groups in adjacent carbon atoms together with the interconnecting carbon atoms can form a condensed, optionally substituted carbocyclic or heterocyclic ring of 5 or 6 members. |