| abstract |
Indazole compounds that modulate and / or inhibit the activity of protein kinases are described. These compositions and the pharmaceutical compounds that contain them are capable of mediating kinase dependent diseases to modulate and / or inhibit the proliferation of undesirable cells. The invention is also directed to the Therapeutic or prophylactic use of Pharmaceutical compositions containing these compounds and to the methods of cancer treatment as well as to other Diseases associated with angiogenesis and / or undesirable cell proliferation, such as diabetic retinopathy, neovascu1ar glaucoma, rheumatoid arthritis and psoriasis, with the effective administration of these compounds. |