abstract |
1H-Imidazole and 1H-1,2,4-triazole derivatives of the formula <IMAGE> in which Q denotes CH or N, Ar denotes phenyl, thienyl, halogenthienyl or phenyl which is substituted by from 1 to 3 substituents selected from halogen, lower alkyl, lower alkoxy and trifluoromethyl, and Y is selected specifically from 1H-pyrrol-1-yl, 1H-pyrazol-1-yl, 1H- imidazol-1-yl, 1H-1,2,4-triazol-1-yl, 4H-1,2,4-triazol-4- yl, 2,3-dihydro-4H-1,2,4-triazol-4-yl and 1H-1,2,3,4- tetrazol-1-yl radicals, or acid addition salts and stereochemically isomeric forms thereof, are prepared by a number of different processes. The compounds possess antifungal and antibacterial activity. Compounds of the formula <IMAGE> can be used as intermediates for preparing compounds of the formula I and also possess antifungal and antibacterial activity. <IMAGE> |