| abstract |
New peptides (I) have immunological properties in common with those of the peptide skeleton of the envelope protein of HIV-2 and also have a peptide structure in common with that of SIV (simian immunodeficiency virus)-7 glycoprotein. Also new are (i) a sequence of 9600 nucleotides corresponding to the SIV genome (reproduced in the specification, together with derived amino acid sequence of viral proteins gag, pol, env, Q, X, R, tat, art and F genes) and its fragments; (2) recombinant DNA contg. all or part of the CDNA from this sequence inserted into a vector, and (3) antigenic and immunogenic conjugates contg. (I). |