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filingDate 1990-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2005-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f98bd164511140289951279ff6041ed
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publicationDate 2005-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber DK-175853-B1
titleOfInvention Secretory leader sequences
abstract Secretory leader sequences, for use in secreting heterologous polypeptides in yeast, are formed by fusing part of the human serum albumin pre-sequence or part of the Kluyveromyces lactis killer toxin pre-sequence to the Saccharomyces cerevisiae mating factor alpha-1 KEX2 cleavage recognition site. The resulting fusion leader sequences are: (a) H2N-Met-Lys-Trp-Val-Ser-Phe-Ile-Ser-Leu-Leu-Phe-Leu-Phe-Ser-Ser-Ala-Tyr-Ser-Arg-Ser-Leu-Asp-Lys-Arg-COOH or (b) H2N-Met-Asn-Ile-Phe-Tyr-Ile-Phe-Leu-Phe-Leu-Leu-Ser-Phe-Val-Gln-Gly-Ser-Leu-Asp-Lys-Arg-COOH Conservative variations are also encompassed.
priorityDate 1988-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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