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filingDate 1997-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2004-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2004-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber DE-69721247-T2
titleOfInvention WATER-SOLUBLE TRI-SUBSTITUTED 1,2-DIOXETANE COMPOUNDS WITH INCREASED STORAGE STABILITY, SYNTHESIS PROCEDURE AND INTERMEDIATE CONNECTIONS
abstract Stable, enzymatically triggered chemiluminescent 1,2-dioxetanes with improved water solubility and storage stability are provided. Dioxetanes further substituted with two or more water-solubilizing groups disposed on the dioxetane structure and an additional fluorine atom or lower alkyl group provide superior performance by eliminating the problem of reagent carryover when used in assays performed on capsule chemistry analytical systems. These dioxetanes display substantially improved stability on storage. Compositions comprising these dioxetanes, a non-polymeric cationic surfactant enhancer and optionally a fluorescer, for providing enhanced chemiluminescence are also provided.
priorityDate 1996-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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