http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-69530511-T2

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filingDate 1995-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2004-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5453d42f55d91ce59b86bd92994fe71b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a9e16271118fc19add216ff828d9a0da
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publicationDate 2004-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber DE-69530511-T2
titleOfInvention ENANTIOSELECTIVE PRODUCTION OF PHARMACEUTICALLY ACTIVE SULFOXIDES BY BIOREDUCTION
abstract PCT No. PCT/SE95/01416 Sec. 371 Date Dec. 18, 1995 Sec. 102(e) Date Dec. 18, 1995 PCT Filed Nov. 27, 1995A compound of formula (II), either as a single enantiomer or in an enantiomerically enriched form <IMAGE> (II) wherein: <IMAGE> and <IMAGE> <IMAGE> (wherein N in the benzimidazole moiety of Het2 means that one of the carbon atoms substituted by any one of R6 to R9 optionally may be exchanged for an unsubstituted nitrogen atom; R1, R2 and R3 are the same or different and selected from hydrogen, alkyl, alkoxy optionally substituted by fluorine, alkylthio, alkoxyalkoxy, dialkylamino, piperidino, morpholino, halogen, phenylalkyl, phenylakoxy; R4 and R4, are the same or different and selected from hydrogen, alkyl, aralkyl; R5 is hydrogen, halogen, trifluoromethyl, alkyl, alkoxy; R6 -R9 are the same or different and selected from hydrogen, alkyl, alkoxy, halogen, haloalkoxy, alkylcarbonyl, alkoxycarbonyl, oxazolyl, trifluoroalkyl or adjacent groups R6 -R9 may complete together with the carbon atoms to which they are attached optionally substituted ring structures; R10 is hydrogen or alkoxycarbonyloxymethyl; R11 is hydrogen or forms an alkylene chain together with R3; R12 and R13 are the same or different and selected from hydrogen, halogen or alkyl) is obtained by stereoselective bioreduction of a compound of formula (II) in racemic form.
priorityDate 1994-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Predicate Subject
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Total number of triples: 29.