| abstract |
A process for the preparation of 1-Ä(cyano)aryl methylÜcyclohexanol of the general formula 1 (1a-d) by reacting cyclohexanone with the carbanions of an aryl acetonitrile of the general formula 3 (3a-d), <CHEM> a) R1 = H, R2 = H b) R1 = OMe, R2 = H c) R1 = OMe, R2 = OMe d) R1 = OMe, R2 = cyclopentyloxy using a base, preferably Na OH or KOH, at a temperature in the range of 0-15 DEG C for a time period in the range of 15 minutes to 120 minutes, isolating the compund of formula 1 and purifying the compund of formula 1a-d by crystallisation. |