| abstract |
A compound represented by the formula (I): <CHEM> or a salt thereof exhibits excellent inhibitory activity of lipid peroxidation and is useful as an agent for inhibiting lipoperoxide production, wherein A ring denotes a non-aromatic 5- to 7-membered nitrogen-containing heterocyclic ring which may be further substituted, B ring denotes a benzene ring which may be further substituted, C ring denotes a dihydrofuran ring which may be further substituted, and R denotes hydrogen atom or an acyl group, provided that: (1) when A ring is a non-aromatic 5-membered nitrogen-containing heterocyclic ring substituted with a group represented by the general formula: -(CH2)m-N(R")-C(=C)-R' (wherein R' denotes an optionally substituted hydrocarbon group, an optionally substituted amino group, or an optionally substituted heterocyclic group, R" denotes hydrogen atom or an optionally substituted hydrocarbon group, and m is an integer of 1 to 4), B ring denotes an further substituted benzene ring, and (2) when A ring denotes a non-aromatic 6-membered nitrogen-containing oxo-substituted heterocyclic ring, B ring denotes a wholly substituted benzene ring. |