| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f19606cd67c29eec9b2eeeea31dbb71f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a75461b1061c9be6ef624da0d4be5a32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3ddcb119ffd4000063622107936241e4 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2531-822
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2231-645 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J31-188
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J31-1875
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-55 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-24 |
| filingDate |
1994-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bdfb0a92b8a873e04c2dfc7a013f9c6a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c049a4c8dfe4ba64088196a64f19e15b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01dc5a72e53d931208c9783e7ee3e2b4 |
| publicationDate |
1996-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
DE-4434293-A1 |
| titleOfInvention |
Process for the preparation of pyridylalanines and their derivatives by means of catalytic asymmetric hydrogenation |
| abstract |
Prepn. of 3- and 4-pyridyl alanine and its. derivs. by catalytic asymmetric hydrogenation comprises reacting 2-acetylamino-, or 2-benzoylamino- -3-(3- or 4-pyridyl) acrylic acid methyl esters of formula (I) or (II) with H2 in the presence of a rhodium complex catalyst of formula (III) and in the presence of 1-5 mol HBF4 per mole substrate. R = H or Me; R1 = Ph or Me; A = (S)-(+)-PROPRAPHOS, (R)-(-)-PROPRAPHOS or (S,S)-(+)-(a) (a) is of formula (a): PROPRAPHOS = 2,3-O,N-bis/diphenyl; phosphino)-naphthoxy-2- hydroxy-3-isopropylamino propane. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03022834-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6967253-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7176223-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010522733-A |
| priorityDate |
1994-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |