http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-4430592-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9911f3ffb183144488431472d9039dfa |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T428-2984 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1277 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-133 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-28 |
| filingDate | 1994-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e5310a5ea999d4af2e84ff78444dee1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ab57e2f7faa5fddbc7083403f915492 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a271fa5afdf75c8e277a3e6ea506daf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_daed3db603f5d54026c31b73f3bcb187 |
| publicationDate | 1996-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DE-4430592-A1 |
| titleOfInvention | Liposomal preparation, its preparation and its use |
| abstract | The liposomal preparation proposed is suitable for use in pharmaceutics and medicine, in particular as a carrier for drugs, vaccines, diagnostic agents and vectors. Its production and use are also disclosed. The liposomes in the preparation proposed are exclusively, or to by far the greater part, unilamellar liposomes of small to medium size, preferably 10 t0 300 nm in diameter, with a closely packed vesicular structure. A high proportion, preferably at least 20 %, of the active substance is included in the preparation in encapsulated form. The preparation can be used directly as a depot of the encapsulated substance, or after stepwise dilution by addition of an aqueous solution. The preparation is produced by mixing a lipid or lipids, water and the active substance to be incorporated, and subsequently removing the solvents by evaporation and dispersal in water, followed by single or multiple high-pressure homogenization (at the most 50 times) at a pressure between 50 and 1600 bar (5-160 MPa) and, optionally, freeze/thaw treatment. The preparation is then converted into a free-flowing dispersion which is extruded through filters with a pore size of 0.1 to 1 mu m. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2601934-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2210589-A1 |
| priorityDate | 1994-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.