| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_12a9e9ce63eb0bbf3658453fb50a6d9b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10343
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-13043 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-503
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-015
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-075
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-00 |
| filingDate |
1994-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53725b23ef6840eb26d297cea129a1c4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ebbc3bf6c9f735f4892071eb16e46bd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_23c54cda2cac6e8968d41bbaf4424d2d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9834ca9017ea2e2e8ea242ddaf0c41dc |
| publicationDate |
1996-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
DE-4426429-A1 |
| titleOfInvention |
Method for introducing DNA into higher eukaryotic cells |
| abstract |
The invention concerns a process for preparing viruses and viral vectors by the transfection of mammal cells with complexes of viral DNA and a polycation, which is optionally conjugated with a ligand for the target cell, in the presence of an endosomolytic agent. The process affords particular advantages for the production of recombinant retroviruses, adenoviruses and adeno-associated viruses in the cell, permitting high virus titres in packing cell lines and in primary cells. The area of application is above all gene therapy. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6358524-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-19605279-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5916803-A |
| priorityDate |
1994-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |