| abstract |
New substituted arylsulfonamides are disclosed having the general formula (I), in which A and R1 to R8 have the definition given in the first claim, as well as their stereoisomers, their mixtures and their salts, in particular their physiologically acceptable salts with inorganic or organic acids or bases. These compounds have valuable pharmacological properties, in particular a thrombin-inhibiting effect and a thrombin-retarding effect. Also disclosed are medicaments containing these compounds, their use and their preparation. |