| abstract |
Carbamoyl carboxylic acid hydrazide derivs. of formula (I) and their salts are new: R<1> = 1-8 C alkyl, 2-8 C alkenyl or 2-8 C alkynyl (these 3 gps. each opt. partially or completely halogenated and/or mono-, di- or tri-substd. by T gps.), 3-7 C cycloalkyl or 4-7 C cycloalkenyl (these 2 gps. each opt. partially or completely halogenated and/or mono-, di- or tri-substd. by U gps. or aryl (1-4 C) alkyl,etc.; R<2>,R<5> = 1-8 C alkyl or 3-7 C cycloalkyl, etc.;R<3>,R<4> = 1-8 C alkyl (opt. mono-, di- or tri-substd. by halo, CN, 1-4 C alkoxy, etc.;R<3> and R<4> together with the C atom to which they are attached form a 4-8 membered ring (contg. in addition to C ring members,1 or 2 heteroatoms e.g. O,S, etc.);R<6>=H or as R<1>,except T and U gps. do not include 1-4C alkoxy carbonyl;R<7>= as R<6> but is not H;T = CN, 1-4 C alkoxy, 1-4 C haloalkoxy, etc.;U = CN, 1-4 C alkyl, 1-4 C alkoxyalkyl, etc..The following cpds. are excluded, e.g. (Ia)-(Id), where R<1> = PhCH2; R<2> = H; R<3> = Me, n-Pr, i-Pr or PhCH2; R<4> = R<5>=H; R<6>=R<7>=CH2CH2Cl; etc.. |