http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-4418825-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_12a9e9ce63eb0bbf3658453fb50a6d9b |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10322 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4747 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-87 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-79 |
| filingDate | 1994-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_23c54cda2cac6e8968d41bbaf4424d2d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4b292b0a2cffb2e4873b32b7ea2171d |
| publicationDate | 1995-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DE-4418825-A1 |
| titleOfInvention | Method for introducing foreign material into higher eukaryotic cells |
| abstract | Process for introducing foreign material, e.g. nucleic acids, into higher eukaryotic cells comprises introducing the foreign material and transfection components into the cells and: (a) introducing \- 1 nucleic acid (esp. DNA) mol. whose expression prods. at least partially block apoptosis induced by introduction of the foreign material and/or (b) at least partially inhibiting the inflammatory response to the cells by (i) treating the cells externally with \- 1 antiinflammatory substance and/or (ii) introducing \- 1 antiinflammatory substance, or nucleic acid (esp. DNA) mol., coding for such substances, into the cells. Also claimed is a transfection complex comprising: (1) a nucleic acid mol. to be expressed in a target cell, where the nucleic acid is complexed with a polycation and the polycation is opt. conjugated with a ligand for the target cell; (2) an adenovirus or an adenovirus-polycation conjugate, and (3) a DNA mol. with anti-apoptotic activity and/or a DNA mol. coding for a substance with antiinflammatory activity. |
| priorityDate | 1994-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 436.