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filingDate 1993-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b0f85662d84add1264e1a0cf66f5a462
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publicationDate 1995-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber DE-4334154-A1
titleOfInvention 2-halo-1,25-dihydroxy-cholecalciferols, pharmaceutical agents, for use as medicaments and process for the preparation of cholecalciferols
abstract 2-Halo-1,25-dihydroxycholecalciferols, of the formula I <IMAGE> wherein X = chlorine or bromine and R1 = hydrogen or C1-C9-alkanoyl or benzoyl, and processes for their preparation. In addition to their vitamin D activity, the compounds have proliferation-inhibiting and cell-differentiating actions, that with respect to the cell differentiation being strongly dissociated compared with the hypercalcaemic action. The compounds are suitable for the preparation of medicaments.
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