abstract |
Compounds of the formula I <IMAGE> in which R1 is an alkyl, cycloalkyl, aryl, heteroaryl or aralkyl group, it being possible for the aryl or heteroaryl radicals to be mono- or polysubstituted by halogen, nitrile, alkyl, trifluoromethyl, alkoxy, alkylthio, alkylsulphinyl, alkylsulphonyl, trifluoromethoxy, hydroxyl, carboxyl, hydroxyalkyl, carboxyalkyl, alkoxycarbonyl or aminocarbonyl, R2 is a hydrogen atom, or an alkyl, cycloalkyl, alkenyl, alkynyl or aralkyl group, R3 and R4 are identical or different and are hydrogen atoms or alkyl groups and R5 is a hydrogen or halogen atom, or an alkyl, alkoxy or trifluoromethyl group, and their hydrates, solvates, physiologically tolerable salts and optical isomers, processes for their preparation and medicaments which contain these substances for the treatment of thromboembolic diseases. |