abstract |
A pharmaceutical composition containing an HMG-CoA compound of the formula wherein R is selected from the group of the indolyl, pyrimidinyl, indenyl, pyrazolyl, pyrrolyl, imidazolyl, indolizinyl, pyrrolopyridinyl, pyrazolopyridinyl, quinolinyl, phenylsilylphenyl, naphthyl, cyclohexyl, phenylthienyl, phenylfuryl and pyridazinyl residues and derivatives thereof, X stands for -CH = CH- and M is an alkali metal ion or ammonium, and a pharmaceutically acceptable alkaline medium capable of adjusting a pH of at least 8 in an aqueous solution or dispersion of the agent in intimate admixture with at least one carbonate. |