http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-4244241-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f8dbdfc93841b3d731fbab7ea48b412a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C323-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C257-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C317-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C317-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C317-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C323-62 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C317-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C317-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C317-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C257-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-20 |
| filingDate | 1992-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ef146fa7637a4a87f8c54d0bde1a20d7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fcf7fa805648e14d00a6943859aa637d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c986e906ab9df21e54e6cc5f91313e27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_705dfcdb1f0ce64b7c3252a525c2a3c3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d91f09c86847b02e6efb7dff687ac53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61d2b546009cc3f438a24f1adeb3d967 |
| publicationDate | 1994-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DE-4244241-A1 |
| titleOfInvention | New compounds, their production and their use |
| abstract | Amidine derivs. of formula (I), in the form of their racemates, enantiomer pure or enriched forms, diastereomer pairs, cis- and trans-isomers, free bases or salts (pref. with physiologically acceptable acids) are new. In (I), R1 and R2 are each CF3, halogen, R5, OR5, COR6, SR6, SOR6, SO2R6, SO2NR5R7, C(OH)R5R7, or R1 and R2 connect neighbouring C atoms on the benzene ring to which they are attached with -CR8=CR9CH=CH-, -CH=CR8CR9=CH-, -CR8=CHCR9=CH-, -OCHR10CH2-, -OCH2O-, -OCH2CH2O-, -(CH2)3-4-, -NHCOO-, -NHCOCH2O-, -COCH2O- or -COCH2CH2O-, each of these gps. being opt. substd. with 1-4C alkyl; R3 is H, OH, CF3, R5, OR6, COR6, CONR5R7, CH2OH, CH2O(1-4C alkyl), SR6, SOR6, SO2R6, SO2NR5R7, NHCO(1-4C alkyl), NHSO2(1-4C alkyl), NR5R7 or C(OH)R5R7 or a heterocyclic 5-ring contg. 1-3 heteroatoms and of formulae (a), (b) or (c); provided that if R3 is R5, R5 can only be H if at least one of R1 and R2 is not H; D, E and G are each CH, N, C(1-4C alkyl) or C-Ph; L is O or S; R4 is halogen, NH2, NH(1-4C alkyl), N(1-4C alkyl)2, OH, 1-4C alkoxy; R5 is H, 1-12C alkyl, phenyl(1-4C)alkyl or Ph (opt. substd. with halogen, 1-4C alkyl, 1-4C alkoxy or 2-5C acyl); R6 is 1-12C alkyl, Ph (opt. substd. with halogen, 1-4C alkyl, 1-4C alkoxy or 2-5C acyl); R7 is H or 1-12C alkyl; R8 and R9 are each H, OH, 1-4C alkyl, 1-4C alkoxy or 2-5C acyl; R10 is H or 1-4C alkyl; R11 and R12 are each H, OH, halogen, CF3, 1-4C alkyl or 1-4C alkoxy; A is (d), (e), X1A1X2, X2A2X3, X4A2X2, (CH2)1-2NHCO(CH2)1-3X2, -CH=CHA2X2; B is CH=CH, CH=N, S or (f); A1 is 2-4C alkylene, cis- or trans-CH2CH=CHCH2, CH2CCCH2, etc.; A2 is 1-5C alkylene; X1 is O, NH, S, SO, SO2, CO, CH2 or a gp. of formula (d); X2 is O, NH, S or a gp. of formula (e); X3 is NHCO, CONH, SO2NH or a gp. of formula (d); X4 is NHCO, CONH, NHSO2, SO2NH or NHCONH. |
| priorityDate | 1992-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 56.