http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-4240219-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cacd77b97a8428d219a1e8c2c9db5c63 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C309-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C309-73 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C43-1782 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C43-1787 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D319-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C303-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C303-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C309-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D319-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C309-73 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C43-178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C303-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C303-30 |
| filingDate | 1992-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_adff2c2b870df4b289681f199d10e634 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7d87248b2aee9d16f6a968cb1278787 |
| publicationDate | 1994-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DE-4240219-A1 |
| titleOfInvention | Process and intermediates for the production of ceramide 3 and related compounds |
| abstract | Prepn. of 2-O-sulphonyl or 2-O-sulphato-tetrol derivs. of formula (I) comprises: (a) reacting a 1,3-O-protected tetrol of formula (IIa) with a sulphonylating or sulphating agent and then removing the 1,3-O-protecting gp. from the resulting 2-O-sulphonate or 2-O-sulphate of formula (IV); or (b) hydrogenating the double bond in a 2-O-sulphonyl or 2-O-sulphatotetrol-6-ene of formula (XV); or (c) activating the free 2-O-hydroxyl gp. of a tetrol of formula XVIII by reaction with a sulphonylating or sulphating agent. The protecting gp. R3 is then opt. removed or opt. introduced, as necessary. R1 = 5-19C alkyl opt. contg. OH gps. Me side chains and double bonds; R2 = lower aliphatic or monocyclic opt. substd. aromatic sulphonic acid or sulphate; R3 = H or hydroxy protecting gp.; R4, R5 = H, lower alkyl or opt. substd. aryl. USE/ADVANTAGE - (I) and the other cpds. are intermediates in the prepn. of ceramide 3 and related cpds. which are key components in building barrier layers in the stratum corneum in plants and animals and can be used e.g. in skin-care and hair-care products. The process is diastereospecific, and gives (I) in D-arabino config. starting ultimately from D-arabinose, D-galactose or D-xylose, using relatively few steps. |
| priorityDate | 1992-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 188.